Name: S4 (Andarine)
CAS No.: 401900-40-1
Other Name: S-3-(4-acetylamino-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide;N-[4-Nitro-3-(trifluoromethyl)phenyl]-(2S)-3-[4-(acetylamino)phenoxy]-2-hydroxy-2-methylpropanamide;Ostarine;(2R)-3-(4-Cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide;MK-2866;Andarine;Propanamide,3-[4-(acetylamino)phenoxy]-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phe nyl]-,(2S)-;sarM s4
Appearance: Pale yellow solid
Melting point: 70-74ºC
Boiling Point: 698.735ºC at 760 mmHg
Storage temp.: 2-8ºC
It is a potent and tissue-selective androgen receptor modulator (SARM) used as antiosteoporotic agent.Andarine (401900-40-1) is an orally active partial agonist for androgen receptors. Andarine (401900-40-1) 99.5% or Andarine 401900-40-1, Andarine (Sarm S4) 99.5% are the most common form of andarine. In an animal model of benign prostatic hypertrophy, andarine was shown to reduce prostate weight with similar efficacy to finasteride, but without producing any reduction in muscle mass or anti-androgenic side effects.sarms s-4 andarine cas 401900-40-1
Andarine (401900-40-1) is able to competitively block binding of dihydrotesarms s-4 andarine cas 401900-40-1stosterone to its receptor targets in the prostate gland, but its partial agonist effects at androgen receptors prevent the side effects associated with the anti-androgenic drugs traditionally used for treatment of BPH.
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
Andarine, commonly known as S4, is a Selective Androgen Receptor Modulator (SARM) developed by GTx. Like all SARM’s S4 was developed in the treatment of muscle wasting diseases with benign prostatic hypertrophy treatment also being high on the list of possible treatment benefits. Andarine is not as strong as some of the other SARM’s in terms of an anabolic effect that leads to the promotion of lean muscle tissue increases, but it does appear to have other benefits that can prove to be highly valuable. Being an effective SARM, like most SARM’s it is relatively side effect friendly with most users making it an increasingly common option for performance enhancing athletes.
Anadarine (S4) is a SARM, specifically a medication that binds firmly to the androgen receptors. Unlike an anabolic androgenic steroid, S4 focuses only on the bone and muscle sites unlike other androgenic compounds that may affect secondary sex organs. By binding to the androgen receptors, S4 alters the gene expression, thereby increasing anabolism via increases in protein synthesis. Although a highly effective compound, in comparison to its binding affinity it is approximately one third that of testosterone.
Andarine (S4), unlike many androgens, does not convert to dihydrotestosterone (DHT) and it does not aromatize. Aromatization refers to the conversion of testosterone to estrogen. This makes S4 a bit more appealing on a functional basis compared to other androgenic compounds as negative DHT and Estradiol effects cannot occur with this compound. In fact, S4 has been shown to block DHT from binding to the prostate receptor sites.
S4 is based off of the same template molecularly as the drug Bicalutamide, an anti-androgen. However, unlike Bicalutamide, the severe negative effects of that drug are not present with Andarine – while a similar template it is not the same drug.
|S4 (Andarine, GTX-007)