|Place of Origin:||SHANGHAI|
|Minimum Order Quantity:||10grams|
|Delivery Time:||3 workdays|
|Payment Terms:||Western Union, T/T, MoneyGram, Bitcoin|
|Boiling Point:||868.9ºC At 760 MmHg||Flash Point:||479.3ºC|
Name: MK-677 (Ibutamoren)
CAS No.: 159752-10-0
Other Name: MK-677;2-Amino-N-[(1R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-indole-3,4'-piperidin]-1'-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methylpropanamide methanesulfonate;(R)-1'-(2-Methylalanyl-O-benzyl-D-seryl)-1-(Methylsulfonyl)-1,2-dihydrospiro[indole-3,4'-piperidine] Mesylate;Crescendo;IbutaMoren Mesylate(MK-677);MK-667;N-[1(R)-1,2-Dihydro-1-methanesulfonylspiro-3H-indole-3,4′-piperidin)-1′-yl]carbonyl-2-(phenylmethoxy)-ethyl-2-amino-2-methylpropanamide methanesulfonate;IBUTAMORIN
Appearance: Crystalline powder
Boiling Point: 868.9ºC at 760 mmHg
Flash point: 479.3ºC
Storage temp.: 2-8ºC
Ibutamoren (INN) (developmental code names MK-677, MK-0677, L-163,191) is a non-peptidic, potent, long-acting, orally-active, and selective agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin. It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including GH and insulin-like growth factor 1 (IGF-1), but without affecting cortisol levels. It is currently under development as a potential treatment for reduced levels of these hormones, such as in children or elderly adults with growth hormone deficiency, and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly. It also alters metabolism of body fat and so may have application in the treatment of obesity.
Ibutamoren, also known as MK-677,is a drug which acts as a potent, orally active growth hormone secretagogue, mimicking the GH stimulating action of the endogenous hormone ghrelin.
Studies have shown that this drug is highly potential in increasing bone turnover. When given to elderly subjects, It growth hormone secretagogue was seen to be efficiently improving the condition of bone turnover in them, based on elevations of biochemical markers of bone formation and resorption in them. All this was observed when this peptide was given to them orally.
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